Solution
Solution 1

Let Q(x)=x2−2x+2, R(x)=2x2−4x+3. Completing the square, we have Q(x)=(x−1)2+1, and R(x)=2(x−1)2+1, so it follows that P(x)≥Q(x)≥1 for all x (by the Trivial Inequality).
Also, 1=Q(1)≤P(1)≤R(1)=1, so P(1)=1, and P obtains its minimum at the point (1,1). Then P(x) must be of the form c(x−1)2+1 for some constant c; substituting P(11)=181 yields c=59. Finally, P(16)=59⋅(16−1)2+1=406.
Solution 2
It can be seen that the function P(x) must be in the form P(x)=ax2−2ax+c for some real a and c. This is because the derivative of P(x) is 2ax−2a, and a global minimum occurs only at x=1 (in addition, because of this derivative, the vertex of any quadratic polynomial occurs at 2a−b). Substituting (1,1) and (11,181) we obtain two equations:
P(11)=99a+c=181, and P(1)=−a+c=1.
Solving, we get a=59 and c=514, so P(x)=59x2−518x+514. Therefore, P(16)=406.
Solution 3
Let y=x2−2x+2; note that 2y−1=2x2−4x+3. Setting y=2y−1, we find that equality holds when y=1 and therefore when x2−2x+2=1; this is true iff x=1, so P(1)=1.
Let Q(x)=P(x)−x; clearly Q(1)=0, so we can write Q(x)=(x−1)Q′(x), where Q′(x) is some linear function. Plug Q(x) into the given inequality:
x2−3x+2≤Q(x)≤2x2−5x+3
(x−1)(x−2)≤(x−1)Q′(x)≤(x−1)(2x−3), and thus
x−2≤Q′(x)≤2x−3
For all x>1; note that the inequality signs are flipped if x<1, and that the division is invalid for x=1. However,
limx→1x−2=limx→12x−3=−1,
and thus by the sandwich theorem limx→1Q′(x)=−1; by the definition of a continuous function, Q′(1)=−1. Also, Q(11)=170, so Q′(11)=170/(11−1)=17; plugging in and solving, Q′(x)=(9/5)(x−1)−1. Thus Q(16)=390, and so P(16)=406.
Solution 4
Let Q(x)=P(x)−(x2−2x+2), then 0≤Q(x)≤(x−1)2 (note this is derived from the given inequality chain). Therefore, 0≤Q(x+1)≤x2⇒Q(x+1)=Ax2 for some real value A.
Q(11)=102A⇒P(11)−(112−22+2)=100A⇒80=100A⇒A=54.
Q(16)=152A=180⇒P(16)−(162−32+2)=180⇒P(16)=180+226=406
Solution 5
Let P(x)=ax2+bx+c. Plugging in x=1 to the expressions on both sides of the inequality, we see that a+b+c=1. We see from the problem statement that 121a+11b+c=181. Since we know the vertex of P(x) lies at x=1, by symmetry we get 81a−9b+c=181 as well. Since we now have three equations, we can solve this trivial system and get our answer of 406.
Solution 6
Similar to Solution 5, let P(x)=ax2+bx+c. Note that (1,1) is a vertex of the polynomial. Additionally, this means that b=−2a (since 2a−b is the minimum x point). Thus, we have P(x)=ax2−2ax+c. Therefore a−2a+c=1. Moreover, 99a+c=181. And so our polynomial is 59x2−518x+514. Plug in x=16 to get 406.
Solution 7
Very similar to Solution 6, start by noticing that P(x) is between two polynomials, we try to set them equal to find a point where the two polynomials intersect, meaning that P(x) would also have to intersect that point (it must be between the two graphs). Setting x2−2x+2=2x2−4x+3, we find that x=1. Note that both of these graphs have the same vertex (at x=1), and so P(x) must also have the same vertex (1,1). Setting P(x)=ax2−2ax+a+1 (this is where we have a vertex at (1,1)), we plug in 11 and find that a=1.8. Evaluating 1.8x2−3.6x+2.8 when x=16 (our intended goal), we find that P(16)=406.